DBS Implant and Accessories

DBS Rechargeable Vercise Genus R16 with Directional Lead with minimum 25yr battery life & Image guided programming integrated inside clinician Programmer with MICC “multiple independent current control” technology with 17 independent power sources, it should offer Current steering with monopolar as well as bipolar settings, directional bipolar, Zero Volt Technology, Bluetooth Connectivity with typical range from 9ft to 19ft , USFDA & CE Approved Rechargeable Battery-1 , Directional lead Kit -2 , Extension Kit -2 , Burr hole cover -2 , Tunneling tool -2 , Remote Control Kit -1, Charging Kit -1

DBS Rechargeable Vercise Genus R16 with Non directional lead with minimum 25yr battery life & Image guided programming integrated inside clinician Programmer MICC “multiple independent current control” technology with 17 independent power sources, it should offer Current steering with monopolar as well as bipolar settings, Zero Volt Technology, Bluetooth Connectivity with typical range from 9ft to 19ft have 8 Contact non-directional Lead Kit with Array span of 15.5mm for maximum coverage, USFDA & CE Approved Rechargeable Battery-1 , non-directional lead Kit -2 , Extension Kit -2 , Burr hole cover -2, Tunneling tool -2, Remote Control Kit -1, Charging Kit -1

DBS Non rechargeable Vercise Genus P16 with Directional Lead with Image guided programming integrated inside clinician Programmer MICC “multiple independent current control” technology with 17 independent power sources, it should offer Current steering with monopolar as well as bipolar settings, directional bipolar, Zero Volt Technology, Bluetooth Connectivity with typical range from 9ft to 19ft , USFDA & CE Approved Non-Rechargeable Battery-1 , Directional lead Kit -2 , Extension Kit -2 , Burr hole cover -2 , Tunneling tool -2 , Remote Control Kit -1

DBS Non rechargeable Vercise Genus P16 with non-directional Lead with Image guided programming integrated inside clinician Programmer MICC “multiple independent current control” technology with 17 independent power sources, it should offer Current steering with monopolar as well as bipolar settings, Zero Volt Technology, Bluetooth Connectivity with typical range from 9ft to 19ft have 8 Contact non-directional Lead Kit with Array span of 15.5mm for maximum coverage, USFDA & CE Approved Non-Rechargeable Battery-1, non-directional lead Kit -2, Extension Kit -2, Burr hole cover -2, Tunneling tool -2, Remote Control Kit -1

DBS Rechargeable Replacement kit Vercise Genus R16 (Boston Scientific to Boston Scientific Device Replacement) Rechargeable battery -1 , Patient Charging Kit -1

DBS Rechargeable Replacement kit Vercise Genus R16 with M8 Adapter (Medtronic to Boston Scientific Device Replacement) Rechargeable battery -1 , Patient Remote Control Kit -1, Patient Charging Kit -1, M8 adapters -02

DBS non-rechargeable replacement kit Vercise Genus P16 with M8 adapter (Medtronic to Boston Scientific Device) Non-Rechargeable battery -1 , Patient Remote Control Kit -1, M8 adapters -02

DBS implant Kit with non rechargeable, 3T MRI compatible and sensing enabled IPG and directional leads. • The implanted pulse generator (DBS neurostimulator- IPG) should have a minimum service life of 5-7 years and there should not be a need to recharge it periodically. • IPG should have the capability for group programming and ability to store the programming data in IPG itself and retrieve from IPG. • The system should be able to sense Local Field Potentials (LFPs) from brain targets and this data should be accessible through the physician programmer • The leads should be able to stimulate in specific directions, in addition to the ability to stimulate circumferentially. Markers on leads should facilitate directional programming even if lead rotates. The leads should also be able to sense LFPs. •Burrhole kit should be there for securing lead in place. • Microelectrodes for intra op stimulation and recording should be there. • The extension connecting the lead and IPG should be flexible • There should be a tunneller to place the extension wire and the tunneller should be metallic and firm to enable smooth tunnelling. • The system should have approval for conditional full-body 1.5T & 3 T MRI Compatibility. • Patient programmer, enabling the patient to see and if needed, modify the stimulation under guidance, should be available. Patients should be able to mark dyskinesia, tremor etc. using the programmer.

DBS implant Kit with rechargeable, 1.5T & 3T MRI compatible and sensing enabled IPG and directional leads • The implantable pulse generator (DBS neurostimulator- IPG) should have a service life of 15+ years if regularly recharged by the patient at specified intervals. • IPG should have the capability for group programming and ability to store the programming data in IPG itself and retrieve from IPG. • The system should be able to sense Local Field Potentials (LFPs) from brain targets and this data should be accessible through the physician programmer • The system should have FDA approval for adaptive DBS . • The system should be able to identify the best contact for stimulation based on the LFP data. • The leads should be able to stimulate in specific directions, in addition to the ability to stimulate circumferentially. Markers on leads should facilitate directional programming even if lead rotates. The leads should also be able to sense LFPs. • The system should be able to predict the recharging intervals. • The extension connecting the lead and IPG should be flexible • There should be a tunneller to place the extension wire and the tunneller should be metallic and firm to enable smooth tunnelling • The system should have approval for conditional full-body 3 T MRI Compatibility. • Patient programmer, enabling the patient to see and if needed, modify the stimulation under guidance, should be available. Patients should be able to mark dyskinesia, tremor etc. using the programmer • Burrhole kit should be there for securing lead in place. • Microelectrodes for intra op stimulation and recording should be there.

DBS implant Kit with non rechargeable,1.5T & 3T MRI compatible and sensing enabled IPG and conventional ring mode (non-directional) 4- electrode-contact leads •The implanted pulse generator (DBS neurostimulator- IPG) should have a minimum service life of 3-5 years and there should not be a need to recharge it periodically. • IPG should be capable of group programming and have the ability to store the programming data in IPG itself and retrieve from IPG. • IPG should be able to sense Local Field Potentials • Leads should have four ring-shaped (non-directional) lead contacts; should be able to deliver stimulation circumferentially. • The extension connecting the lead and IPG should be flexible • There should be a tunneller to place the extension wire and the tunneller should be metallic and firm to enable smooth tunnelling. • Should have approval for conditional full body 3 T Magnetic Resonance Imaging (MRI) Compatibility. • Patient programmer, enabling the patient to see and if needed, modify the stimulation under guidance, should be available. •Microelectrodes for intra op stimulation and recording should be there.